We collected total 3,682 food additives(FDs) with structural information from China,The USA,EU,JECFA (WHO). In this Database,we provide FDs information with structual collections(SMILES) from PubChem,ADI,overlapping source info,Functional Class,PubChem ID and CAS Number. The SMILES may help us with toxicity understanding of FDs combined with our machine learning model. We believe this database a good ways for toxicity exploration of FDs. Note that the Database only provide 3,613 FDs information concerning the decoding issue of SMILES (Including some mixtures).