We collected 1,563 chemicals that experimentally have impact on zebrafish emybro development by data mining,and this work is aimed at taking these chemicals as training set for Toxicity predicitons. We proceesed these chemicals and excluced some mxitures or unexcepted chemicals for modeling.Finally,1,301 of them were chosen for training the model as displayed as follows. Except for that, We gathered chemicals that have relations with developmental cardiac toxicity and neurotoxicity with 1,232 and 1,032 chemicals respectively. There are phenotypes in the list including seven abnormal phenotypes(Abnormal hatching,Abnormal Heart Rate,Body Malformation,Body Pigmentation ,Cardiac Edema,Yolk Sac Edema),cardiac toxicity,neurotoxicity and negative(toxicity undetected).